KNCV Tuberculosis Foundation is an international non-profit organization dedicated to fighting tuberculosis (TB) worldwide and to strengthening health systems against TB, globally and locally. The organization is an international center of expertise for TB control. We are an organization of passionate TB professionals; this includes doctors, researchers, training experts, nurses and epidemiologists. We aim to stop the spread of the worldwide epidemic of the second 'killer’ infectious disease and to prevent the further spread of drug-resistant TB. Over the past century we have built up a wealth of knowledge and expertise, initially by succesfully driving back TB in the Netherlands. Since the 1970s we also share our knowledge and expertise with the rest of the world. Our vision is: A world free of tuberculosis. Our mission is: The global elimination of TB through the development and implementation of effective, efficient and sustainable TB control strategies.
Job Title: Project Manager
BPAL Project Background
In December 2019 WHO endorsed the use of the novel BPaL regimen for MDR-TB patients with resistance to fluoroquinolones under operational research conditions.
This 6-9 month regimen was trialled in the Nix-TB study by the TB Alliance for use in patients with XDR-TB or intolerance or failure of an MDR-TB treatment regimen with 89% favorable outcome (culture negative) after 6 months post-treatment follow-up. Due to the high rate of adverse events, the regimen may not yet be considered for programmatic use until more evidence on efficacy and safety has been generated.
The BPaL demonstration pilot project in Nigeria is intended to generate this additional evidence and will ensure the human resource capacity and organization of care, the laboratory network, drug procurement, and supply management system and active drug safety monitoring and management (aDSM) are in place to ensure responsible use of this novel regimen and lay the basis for nationwide scale-up.
Purpose of the Position
The BPAL Project Manager is responsible for the overall implementation of the project including the overarching management responsibilities in the branch office such as governance, HR and security.
Place in the organization
The BPAL Project Manager reports to the Grant Manager at KNCV’s Head Office in The Hague.
As Project Manager you will:
Project Management:
Coordinate collaborative activities of key stakeholders in the piloting of the BPaL;
Support the start-up and implementation of the BPaL project activities in the selected states;
Monitor the BPaL Operational Research and ensure that the reporting requirements are fulfilled;
Organize supportive supervisory and mentoring visits for STTA Consultants from KNCV HQ in collaboration with NTBLCP;
Inventory requirements to set up a separate payroll and accounting system;
Implement a planning and control cycle (including budget, periodic reporting, annual report).
Ensure that people’s rights are protected and that the conduct of the operational research is in compliance with the approved protocol;
Identify constraints in the identification of presumptive MDR-TB patients, sputum examinations, drug susceptibility testing, identification of eligible patients for the BPaL regimen, timely enrolment, pre-treatment assessment, treatment initiation, treatment monitoring, management of AEs, DOT services in the community, contacting of late patients, and treatment outcome assessment;
Supervise data collection by the research assistant and verify that the reported data are complete, timely and accurate;
Provide supportive supervision and ongoing mentoring for clinical staff and treatment supporters, through weekly site meetings;
Organize monthly project meetings to assess the overall performance of the project with the participation of NTBLCP;
Participate in quarterly research committee meeting, with NTBLCP, WHO/TDR and other study partners to review progress of all patients on treatment.
Overarching Management:
Ensure proper execution of the KNCV Country Office manual and HRM manual;
Implement (changes in) relevant policies and procedures in the Country Office as advised by KNCV HO;
Is end responsible for in country KNCV security policy and ensures it is fully operational and adhered to;
Has Country level signatory power on behalf of KNCV as determined in letter of authorization;
Represent KNCV Branch Office externally with partners in country.
Coordination with Local NGO KNCV Nigeria:
Provide the link between the KNCV International (Branch office) and KNCV Nigeria through:
Knowledge and experience sharing;
Cooperation in applying for funds in Nigeria for the shared objective of reducing TB and associated infectious disease within Nigeria and worldwide.
Resource Mobilization:
Identify opportunities for local resource mobilization and ensures required follow up;
Contribute to international resource mobilization in close collaboration with HO;
Lead and oversee in country proposal development activities including budget development, supported by financial staff;
